Cargando…
SAP-controlled T-B cell interactions underlie germinal centre formation
Generation of long-term antibody-mediated immunity depends on the germinal centre (GC) reaction, which requires cooperation between antigen-specific T and B lymphocytes. In the human X-linked lymphoproliferative disease and its gene-targeted mouse model, loss-of-function mutations in signalling lymp...
Autores principales: | Qi, Hai, Cannons, Jennifer L., Klauschen, Frederick, Schwartzberg, Pamela L., Germain, Ronald N. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652134/ https://www.ncbi.nlm.nih.gov/pubmed/18843362 http://dx.doi.org/10.1038/nature07345 |
Ejemplares similares
-
SAP regulates T cell–mediated help for humoral immunity by a mechanism distinct from cytokine regulation
por: Cannons, Jennifer L., et al.
Publicado: (2006) -
The Road Less Taken: Less Appreciated Pathways for Manipulating CD8(+) T Cell Exhaustion
por: Pichler, Andrea C., et al.
Publicado: (2022) -
X-Linked Lymphoproliferative Disease Type 1: A Clinical and Molecular Perspective
por: Panchal, Neelam, et al.
Publicado: (2018) -
Genetic Defects in Phosphoinositide 3-Kinase δ Influence CD8(+) T Cell Survival, Differentiation, and Function
por: Cannons, Jennifer L., et al.
Publicado: (2018) -
PI3K Orchestrates T Follicular Helper Cell Differentiation in a Context Dependent Manner: Implications for Autoimmunity
por: Preite, Silvia, et al.
Publicado: (2019)