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Small Changes in the Primary Structure of Transportan 10 Alter the Thermodynamics and Kinetics of its Interaction with Phospholipid Vesicles

[Image: see text] The kinetics and thermodynamics of binding of transportan 10 (tp10) and four of its variants to phospholipid vesicles, and the kinetics of peptide-induced dye efflux, were compared. Tp10 is a 21-residue, amphipathic, cationic, cell-penetrating peptide similar to helical antimicrobi...

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Detalles Bibliográficos
Autores principales: Yandek, Lindsay E., Pokorny, Antje, Almeida, Paulo F. F.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652248/
https://www.ncbi.nlm.nih.gov/pubmed/18260641
http://dx.doi.org/10.1021/bi702205r