The HLA-DRα Chain Is Modified by Polyubiquitination

Ubiquitination plays a major role in regulating cell surface and intracellular localization of major histocompatibility complex class II molecules. Two E3 ligases, MARCH I and MARCH VIII, have been shown to polyubiquitinate lysine residue 225 in the cytoplasmic tail of I-Aβ and HLA-DRβ. We show that...

Descripción completa

Detalles Bibliográficos
Autores principales: Lapaque, Nicolas, Jahnke, Martin, Trowsdale, John, Kelly, Adrian P.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652342/
https://www.ncbi.nlm.nih.gov/pubmed/19117940
http://dx.doi.org/10.1074/jbc.M805736200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652342/
https://www.ncbi.nlm.nih.gov/pubmed/19117940
http://dx.doi.org/10.1074/jbc.M805736200

Ejemplares similares