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Synthesis of (+)-Cortistatin A
[Image: see text] Cortistatin A is a marine steroid with highly selective and perhaps mechanistically unique antiangiogenic activity. Herein we report a synthesis of this natural product by way of “cortistatinone”, an intermediate ideally suited for investigating the key pharmacophore of the cortist...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652360/ https://www.ncbi.nlm.nih.gov/pubmed/18479104 http://dx.doi.org/10.1021/ja8023466 |