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Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein

BACKGROUND: SCAR/WAVE proteins couple signalling to actin polymerization, and are thus fundamental to the formation of pseudopods and lamellipods. They are controlled as part of a five-membered complex that includes the tiny HSPC300 protein. It is not known why SCAR/WAVE is found in such a large ass...

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Detalles Bibliográficos
Autores principales: Pollitt, Alice Y, Insall, Robert H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652429/
https://www.ncbi.nlm.nih.gov/pubmed/19228419
http://dx.doi.org/10.1186/1471-2121-10-13