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CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome?

BACKGROUND: CpG islands (CGIs), clusters of CpG dinucleotides in GC-rich regions, are often located in the 5' end of genes and considered gene markers. Hackenberg et al. (2006) recently developed a new algorithm, CpGcluster, which uses a completely different mathematical approach from previous...

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Detalles Bibliográficos
Autores principales: Han, Leng, Zhao, Zhongming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652441/
https://www.ncbi.nlm.nih.gov/pubmed/19232104
http://dx.doi.org/10.1186/1471-2105-10-65