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Short hairpin RNA-mediated knockdown of protein expression in Entamoeba histolytica

BACKGROUND: Entamoeba histolytica is an intestinal protozoan parasite of humans. The genome has been sequenced, but the study of individual gene products has been hampered by the lack of the ability to generate gene knockouts. We chose to test the use of RNA interference to knock down gene expressio...

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Detalles Bibliográficos
Autores principales: Linford, Alicia S, Moreno, Heriberto, Good, Katelyn R, Zhang, Hanbang, Singh, Upinder, Petri, William A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652455/
https://www.ncbi.nlm.nih.gov/pubmed/19222852
http://dx.doi.org/10.1186/1471-2180-9-38