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A new measure of population structure using multiple single nucleotide polymorphisms and its relationship with F(ST)

BACKGROUND: Large-scale genome-wide association studies are promising for unraveling the genetic basis of complex diseases. Population structure is a potential problem, the effects of which on genetic association studies are controversial. The first step to systematically quantify the effects of pop...

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Detalles Bibliográficos
Autores principales: Xu, Hongyan, Sarkar, Bayazid, George, Varghese
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652468/
https://www.ncbi.nlm.nih.gov/pubmed/19284702
http://dx.doi.org/10.1186/1756-0500-2-21