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A new measure of population structure using multiple single nucleotide polymorphisms and its relationship with F(ST)
BACKGROUND: Large-scale genome-wide association studies are promising for unraveling the genetic basis of complex diseases. Population structure is a potential problem, the effects of which on genetic association studies are controversial. The first step to systematically quantify the effects of pop...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652468/ https://www.ncbi.nlm.nih.gov/pubmed/19284702 http://dx.doi.org/10.1186/1756-0500-2-21 |