hVps15, but not Ca(2+)/CaM, is required for the activity and regulation of hVps34 in mammalian cells

The mammalian Class III PI3K (phosphoinositide 3-kinase), hVps34 [mammalian Vps (vacuolar protein sorting) 34 homologue], is an important regulator of vesicular trafficking, autophagy and nutrient sensing. In yeast, Vps34 is associated with a putative serine/threonine protein kinase, Vps15, which is...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Ying, Flinn, Rory J., Wu, Haiyan, Schnur, Rachel S., Backer, Jonathan M.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652830/
https://www.ncbi.nlm.nih.gov/pubmed/18957027
http://dx.doi.org/10.1042/BJ20081865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652830/
https://www.ncbi.nlm.nih.gov/pubmed/18957027
http://dx.doi.org/10.1042/BJ20081865

Ejemplares similares