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Blind search for post-translational modifications and amino acid substitutions using peptide mass fingerprints from two proteases

BACKGROUND: Mass spectrometric analysis of peptides is an essential part of protein identification and characterization, the latter meaning the identification of modifications and amino acid substitutions. There are two main approaches for characterization: (i) using a predefined set of possible mod...

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Detalles Bibliográficos
Autores principales: Barsnes, Harald, Mikalsen, Svein-Ole, Eidhammer, Ingvar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653020/
https://www.ncbi.nlm.nih.gov/pubmed/19099572
http://dx.doi.org/10.1186/1756-0500-1-130