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Normal mitochondrial respiratory function is essential for spatial remote memory in mice

BACKGROUND: Mitochondrial DNA (mtDNA) with pathogenic mutations has been found in patients with cognitive disorders. However, little is known about whether pathogenic mtDNA mutations and the resultant mitochondrial respiration deficiencies contribute to the expression of cognitive alterations, such...

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Detalles Bibliográficos
Autores principales: Tanaka, Daisuke, Nakada, Kazuto, Takao, Keizo, Ogasawara, Emi, Kasahara, Atsuko, Sato, Akitsugu, Yonekawa, Hiromichi, Miyakawa, Tsuyoshi, Hayashi, Jun-Ichi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653021/
https://www.ncbi.nlm.nih.gov/pubmed/19087269
http://dx.doi.org/10.1186/1756-6606-1-21