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Bacterial artificial chromosomes improve recombinant protein production in mammalian cells

BACKGROUND: The development of appropriate expression vectors for large scale protein production constitutes a critical step in recombinant protein production. The use of conventional expression vectors to obtain cell lines is a cumbersome procedure. Often, stable cell lines produce low protein yiel...

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Detalles Bibliográficos
Autores principales: Blaas, Leander, Musteanu, Monica, Eferl, Robert, Bauer, Anton, Casanova, Emilio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653024/
https://www.ncbi.nlm.nih.gov/pubmed/19144171
http://dx.doi.org/10.1186/1472-6750-9-3