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Extended high efficacy of the combination sulphadoxine-pyrimethamine with artesunate in children with uncomplicated falciparum malaria on the Benin coast, West Africa

BACKGROUND: A study carried out in 2003–2005 in Southern Benin showed a day-28 sulphadoxine-pyrimethamine (SP) monotherapy failure rate greater than 40%, while for SP combined with artesunate (SP-AS) the failure rate was 5.3%. Such a large difference could be explained by the relatively short 28-day...

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Detalles Bibliográficos
Autores principales: Nahum, Alain, Erhart, Annette, Ahounou, Daniel, Bonou, Désiré, Van Overmeir, Chantal, Menten, Joris, Akogbeto, Martin, Coosemans, Marc, Massougbodji, Achille, D'Alessandro, Umberto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653068/
https://www.ncbi.nlm.nih.gov/pubmed/19257898
http://dx.doi.org/10.1186/1475-2875-8-37