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Lymphangiosis carcinomatosa in squamous cell carcinomas of larynx and hypopharynx – value of conventional evaluation and additional immunohistochemical staining of D2-40

BACKGROUND: Recent studies revealed a predictive value of lymphatic vessel invasion (L1) for the nodal metastasizing and poor prognosis in malignant tumors at different sites. The monoclonal antibody D2-40 (podoplanin) stains specifically endothelial cells of lymphatic vessels and improves the searc...

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Detalles Bibliográficos
Autores principales: Völker, Hans-Ullrich, Scheich, Matthias, Nowack, Isabell, Metzger, Alexandra, Haubitz, Imme, Puppe, Bernhard, Hagen, Rudolf, Müller-Hermelink, Hans-Konrad, Völter, Christiane
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653073/
https://www.ncbi.nlm.nih.gov/pubmed/19261178
http://dx.doi.org/10.1186/1477-7819-7-25