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Microfludic Device for Creating Ionic Strength Gradients over DNA Microarrays for Efficient DNA Melting Studies and Assay Development

The development of DNA microarray assays is hampered by two important aspects: processing of the microarrays is done under a single stringency condition, and characteristics such as melting temperature are difficult to predict for immobilized probes. A technical solution to these limitations is to u...

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Detalles Bibliográficos
Autores principales: Petersen, Jesper, Poulsen, Lena, Birgens, Henrik, Dufva, Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653225/
https://www.ncbi.nlm.nih.gov/pubmed/19277213
http://dx.doi.org/10.1371/journal.pone.0004808