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Discovery of Novel Hypermethylated Genes in Prostate Cancer Using Genomic CpG Island Microarrays
BACKGROUND: Promoter and 5′ end methylation regulation of tumour suppressor genes is a common feature of many cancers. Such occurrences often lead to the silencing of these key genes and thus they may contribute to the development of cancer, including prostate cancer. METHODOLOGY/PRINCIPAL FINDINGS:...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653233/ https://www.ncbi.nlm.nih.gov/pubmed/19283074 http://dx.doi.org/10.1371/journal.pone.0004830 |