Conformational Flexibility of Metazoan Fatty Acid Synthase Enables Catalysis

The metazoan cytosolic fatty acid synthase (FAS) contains all of the enzymes required for de novo fatty acid biosynthesis covalently linked around two reaction chambers. While the 3D architecture of FAS has been mostly defined, it is unclear how reaction intermediates can transfer between distant ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Brignole, Edward J., Smith, Stuart, Asturias, Francisco J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653270/
https://www.ncbi.nlm.nih.gov/pubmed/19151726
http://dx.doi.org/10.1038/nsmb.1532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653270/
https://www.ncbi.nlm.nih.gov/pubmed/19151726
http://dx.doi.org/10.1038/nsmb.1532

Ejemplares similares