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In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

BACKGROUND: Recently, human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipper factor (HBZ), encoded from a minus strand mRNA was discovered and was suggested to play an important role in adult T cell leukemia (ATL) development. However, there have been no reports on the role of HBZ in patie...

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Detalles Bibliográficos
Autores principales: Saito, Mineki, Matsuzaki, Toshio, Satou, Yorifumi, Yasunaga, Jun-ichirou, Saito, Kousuke, Arimura, Kimiyoshi, Matsuoka, Masao, Ohara, Yoshiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653460/
https://www.ncbi.nlm.nih.gov/pubmed/19228429
http://dx.doi.org/10.1186/1742-4690-6-19