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A module-based analytical strategy to identify novel disease-associated genes shows an inhibitory role for interleukin 7 Receptor in allergic inflammation

BACKGROUND: The identification of novel genes by high-throughput studies of complex diseases is complicated by the large number of potential genes. However, since disease-associated genes tend to interact, one solution is to arrange them in modules based on co-expression data and known gene interact...

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Detalles Bibliográficos
Autores principales: Mobini, Reza, Andersson, Bengt A, Erjefält, Jonas, Hahn-Zoric, Mirjana, Langston, Michael A, Perkins, Andy D, Cardell, Lars Olaf, Benson, Mikael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653464/
https://www.ncbi.nlm.nih.gov/pubmed/19216740
http://dx.doi.org/10.1186/1752-0509-3-19