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A-002 (Varespladib), a phospholipase A(2 )inhibitor, reduces atherosclerosis in guinea pigs

BACKGROUND: The association of elevated serum levels of secretory phospholipase A(2 )(sPLA(2)) in patients with cardiovascular disease and their presence in atherosclerotic lesions suggest the participation of sPLA(2 )enzymes in this disease. The presence of more advanced atherosclerotic lesions in...

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Detalles Bibliográficos
Autores principales: Leite, Jose O, Vaishnav, Ushma, Puglisi, Michael, Fraser, Heather, Trias, Joaquim, Fernandez, Maria Luz
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653470/
https://www.ncbi.nlm.nih.gov/pubmed/19222850
http://dx.doi.org/10.1186/1471-2261-9-7