Predicting genetic interactions with random walks on biological networks

BACKGROUND: Several studies have demonstrated that synthetic lethal genetic interactions between gene mutations provide an indication of functional redundancy between molecular complexes and pathways. These observations help explain the finding that organisms are able to tolerate single gene deletio...

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Detalles Bibliográficos
Autores principales: Chipman, Kyle C, Singh, Ambuj K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653491/
https://www.ncbi.nlm.nih.gov/pubmed/19138426
http://dx.doi.org/10.1186/1471-2105-10-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653491/
https://www.ncbi.nlm.nih.gov/pubmed/19138426
http://dx.doi.org/10.1186/1471-2105-10-17

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