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Predicting genetic interactions with random walks on biological networks
BACKGROUND: Several studies have demonstrated that synthetic lethal genetic interactions between gene mutations provide an indication of functional redundancy between molecular complexes and pathways. These observations help explain the finding that organisms are able to tolerate single gene deletio...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653491/ https://www.ncbi.nlm.nih.gov/pubmed/19138426 http://dx.doi.org/10.1186/1471-2105-10-17 |