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NF-κB activation by Helicobacter pylori requires Akt-mediated phosphorylation of p65

BACKGROUND: The inflammatory response in Helicobacter pylori-infected gastric tissue is mediated by cag pathogenicity island (PAI)-dependent activation of nuclear factor-κB (NF-κB). Phosphatidylinositol 3-kinase (PI3K)/Akt signaling is known to play a role in NF-κB activation, but little information...

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Detalles Bibliográficos
Autores principales: Takeshima, Eriko, Tomimori, Koh, Kawakami, Hirochika, Ishikawa, Chie, Sawada, Shigeki, Tomita, Mariko, Senba, Masachika, Kinjo, Fukunori, Mimuro, Hitomi, Sasakawa, Chihiro, Fujita, Jiro, Mori, Naoki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653507/
https://www.ncbi.nlm.nih.gov/pubmed/19216748
http://dx.doi.org/10.1186/1471-2180-9-36