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Regulation of shear-induced nuclear translocation of the Nrf2 transcription factor in endothelial cells
BACKGROUND: Vascular endothelial cells (ECs) constantly experience fluid shear stresses generated by blood flow. Laminar flow is known to produce atheroprotective effects on ECs. Nrf2 is a transcription factor that is essential for the antioxidant response element (ARE)-mediated induction of genes s...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653516/ https://www.ncbi.nlm.nih.gov/pubmed/19272177 http://dx.doi.org/10.1186/1423-0127-16-12 |