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Regulation of Embryonic Cell Adhesion by the Prion Protein

Prion proteins (PrPs) are key players in fatal neurodegenerative disorders, yet their physiological functions remain unclear, as PrP knockout mice develop rather normally. We report a strong PrP loss-of-function phenotype in zebrafish embryos, characterized by the loss of embryonic cell adhesion and...

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Detalles Bibliográficos
Autores principales: Málaga-Trillo, Edward, Solis, Gonzalo P, Schrock, Yvonne, Geiss, Corinna, Luncz, Lydia, Thomanetz, Venus, Stuermer, Claudia A. O
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653553/
https://www.ncbi.nlm.nih.gov/pubmed/19278297
http://dx.doi.org/10.1371/journal.pbio.1000055