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A Common Variant Associated with Dyslexia Reduces Expression of the KIAA0319 Gene

Numerous genetic association studies have implicated the KIAA0319 gene on human chromosome 6p22 in dyslexia susceptibility. The causative variant(s) remains unknown but may modulate gene expression, given that (1) a dyslexia-associated haplotype has been implicated in the reduced expression of KIAA0...

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Detalles Bibliográficos
Autores principales: Dennis, Megan Y., Paracchini, Silvia, Scerri, Thomas S., Prokunina-Olsson, Ludmila, Knight, Julian C., Wade-Martins, Richard, Coggill, Penny, Beck, Stephan, Green, Eric D., Monaco, Anthony P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653637/
https://www.ncbi.nlm.nih.gov/pubmed/19325871
http://dx.doi.org/10.1371/journal.pgen.1000436