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Signatures of Selection in Fusion Transcripts Resulting From Chromosomal Translocations in Human Cancer

BACKGROUND: The recurrence and non-random distribution of translocation breakpoints in human tumors are usually attributed to local sequence features present in the vicinity of the breakpoints. However, it has also been suggested that functional constraints might contribute to delimit the position o...

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Detalles Bibliográficos
Autores principales: Ortiz de Mendíbil, Iñigo, Vizmanos, José L., Novo, Francisco J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653638/
https://www.ncbi.nlm.nih.gov/pubmed/19279687
http://dx.doi.org/10.1371/journal.pone.0004805