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HIV gp120 Induces, NF-κB Dependent, HIV Replication that Requires Procaspase 8

BACKGROUND: HIV envelope glycoprotein gp120 causes cellular activation resulting in anergy, apoptosis, proinflammatory cytokine production, and through an unknown mechanism, enhanced HIV replication. METHODOLOGY/PRINCIPAL FINDINGS: We describe that the signals which promote apoptosis are also respon...

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Detalles Bibliográficos
Autores principales: Bren, Gary D., Trushin, Sergey A., Whitman, Joe, Shepard, Brett, Badley, Andrew D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653723/
https://www.ncbi.nlm.nih.gov/pubmed/19287489
http://dx.doi.org/10.1371/journal.pone.0004875