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Kin5 Knockdown in Tetrahymena thermophila Using RNAi Blocks Cargo Transport of Gef1

A critical process that builds and maintains the eukaryotic cilium is intraflagellar transport (IFT). This process utilizes members of the kinesin-2 superfamily to transport cargo into the cilium (anterograde transport) and a dynein motor for the retrograde traffic. Using a novel RNAi knockdown meth...

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Detalles Bibliográficos
Autores principales: Awan, Aashir, Bell, Aaron J., Satir, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653729/
https://www.ncbi.nlm.nih.gov/pubmed/19290045
http://dx.doi.org/10.1371/journal.pone.0004873