DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers

Promoter CpG methylation of tumour suppressor genes (TSGs) is an epigenetic biomarker for TSG identification and molecular diagnosis. We screened genome wide for novel methylated genes through methylation subtraction of a genetic demethylation model of colon cancer (double knockout of DNMT1 and DNMT...

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Detalles Bibliográficos
Autores principales: Ying, J, Poon, F F, Yu, J, Geng, H, Wong, A H Y, Qiu, G-H, Goh, H K, Rha, S Y, Tian, L, Chan, A T C, Sung, J J Y, Tao, Q
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653732/
https://www.ncbi.nlm.nih.gov/pubmed/19156137
http://dx.doi.org/10.1038/sj.bjc.6604888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653732/
https://www.ncbi.nlm.nih.gov/pubmed/19156137
http://dx.doi.org/10.1038/sj.bjc.6604888

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