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Enhancement of the activity of phenoxodiol by cisplatin in prostate cancer cells

Phenoxodiol is a novel isoflav-3-ene, currently undergoing clinical trials, that has a broad in vitro activity against a number of human cancer cell lines. Phenoxodiol alone inhibited DU145 and PC3 in a dose- and time-dependent manner with IC(50) values of 8±1 and 38±9 μM, respectively. The combinat...

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Detalles Bibliográficos
Autores principales: McPherson, R A C, Galettis, P T, de Souza, P L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653737/
https://www.ncbi.nlm.nih.gov/pubmed/19209173
http://dx.doi.org/10.1038/sj.bjc.6604920