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Increased tumour dihydroceramide production after Photofrin-PDT alone and improved tumour response after the combination with the ceramide analogue LCL29. Evidence from mouse squamous cell carcinomas

Photodynamic therapy (PDT) has been proven effective for treatment of several types of cancer. Photodynamic therapy alone, however, attains limited cures with some tumours and there is need for its improved efficacy in such cases. Sphingolipid (SL) analogues can promote tumour response in combinatio...

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Detalles Bibliográficos
Autores principales: Separovic, D, Bielawski, J, Pierce, J S, Merchant, S, Tarca, A L, Ogretmen, B, Korbelik, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653738/
https://www.ncbi.nlm.nih.gov/pubmed/19223911
http://dx.doi.org/10.1038/sj.bjc.6604896