Cargando…
Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation
We analysed the effects of small interfering RNA (siRNA)-mediated silencing of Apollon, a member of the inhibitors of apoptosis protein family, on the proliferative potential and ability of human breast cancer cell lines to undergo apoptosis. In wild-type p53 ZR75.1 cells, Apollon knockdown resulted...
Autores principales: | , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653776/ https://www.ncbi.nlm.nih.gov/pubmed/19223905 http://dx.doi.org/10.1038/sj.bjc.6604927 |