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Positional Information Generated by Spatially Distributed Signaling Cascades

The temporal and stationary behavior of protein modification cascades has been extensively studied, yet little is known about the spatial aspects of signal propagation. We have previously shown that the spatial separation of opposing enzymes, such as a kinase and a phosphatase, creates signaling act...

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Detalles Bibliográficos
Autores principales: Muñoz-García, Javier, Neufeld, Zoltan, Kholodenko, Boris N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654021/
https://www.ncbi.nlm.nih.gov/pubmed/19300504
http://dx.doi.org/10.1371/journal.pcbi.1000330