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High-Throughput Detection of Induced Mutations and Natural Variation Using KeyPoint™ Technology
Reverse genetics approaches rely on the detection of sequence alterations in target genes to identify allelic variants among mutant or natural populations. Current (pre-) screening methods such as TILLING and EcoTILLING are based on the detection of single base mismatches in heteroduplexes using end...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654077/ https://www.ncbi.nlm.nih.gov/pubmed/19283079 http://dx.doi.org/10.1371/journal.pone.0004761 |