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High-Throughput Detection of Induced Mutations and Natural Variation Using KeyPoint™ Technology

Reverse genetics approaches rely on the detection of sequence alterations in target genes to identify allelic variants among mutant or natural populations. Current (pre-) screening methods such as TILLING and EcoTILLING are based on the detection of single base mismatches in heteroduplexes using end...

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Detalles Bibliográficos
Autores principales: Rigola, Diana, van Oeveren, Jan, Janssen, Antoine, Bonné, Anita, Schneiders, Harrie, van der Poel, Hein J. A., van Orsouw, Nathalie J., Hogers, René C. J., de Both, Michiel T. J., van Eijk, Michiel J. T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654077/
https://www.ncbi.nlm.nih.gov/pubmed/19283079
http://dx.doi.org/10.1371/journal.pone.0004761