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High-Throughput Detection of Induced Mutations and Natural Variation Using KeyPoint™ Technology
Reverse genetics approaches rely on the detection of sequence alterations in target genes to identify allelic variants among mutant or natural populations. Current (pre-) screening methods such as TILLING and EcoTILLING are based on the detection of single base mismatches in heteroduplexes using end...
Autores principales: | Rigola, Diana, van Oeveren, Jan, Janssen, Antoine, Bonné, Anita, Schneiders, Harrie, van der Poel, Hein J. A., van Orsouw, Nathalie J., Hogers, René C. J., de Both, Michiel T. J., van Eijk, Michiel J. T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654077/ https://www.ncbi.nlm.nih.gov/pubmed/19283079 http://dx.doi.org/10.1371/journal.pone.0004761 |
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