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CFTR Functions as a Bicarbonate Channel in Pancreatic Duct Cells

Pancreatic duct epithelium secretes a HCO(3)(−)-rich fluid by a mechanism dependent on cystic fibrosis transmembrane conductance regulator (CFTR) in the apical membrane. However, the exact role of CFTR remains unclear. One possibility is that the HCO(3)(−) permeability of CFTR provides a pathway for...

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Detalles Bibliográficos
Autores principales: Ishiguro, Hiroshi, Steward, Martin C., Naruse, Satoru, Ko, Shigeru B.H., Goto, Hidemi, Case, R. Maynard, Kondo, Takaharu, Yamamoto, Akiko
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654087/
https://www.ncbi.nlm.nih.gov/pubmed/19204187
http://dx.doi.org/10.1085/jgp.200810122