PIM2 Induced COX-2 and MMP-9 Expression in Macrophages Requires PI3K and Notch1 Signaling

Activation of inflammatory immune responses during granuloma formation by the host upon infection of mycobacteria is one of the crucial steps that is often associated with tissue remodeling and breakdown of the extracellular matrix. In these complex processes, cyclooxygenase-2 (COX-2) plays a major...

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Detalles Bibliográficos
Autores principales: Bansal, Kushagra, Kapoor, Nisha, Narayana, Yeddula, Puzo, Germain, Gilleron, Martine, Balaji, Kithiganahalli Narayanaswamy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654112/
https://www.ncbi.nlm.nih.gov/pubmed/19290049
http://dx.doi.org/10.1371/journal.pone.0004911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654112/
https://www.ncbi.nlm.nih.gov/pubmed/19290049
http://dx.doi.org/10.1371/journal.pone.0004911

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