Factors Influencing the Statistical Power of Complex Data Analysis Protocols for Molecular Signature Development from Microarray Data

BACKGROUND: Critical to the development of molecular signatures from microarray and other high-throughput data is testing the statistical significance of the produced signature in order to ensure its statistical reproducibility. While current best practices emphasize sufficiently powered univariate...

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Detalles Bibliográficos
Autores principales: Aliferis, Constantin F., Statnikov, Alexander, Tsamardinos, Ioannis, Schildcrout, Jonathan S., Shepherd, Bryan E., Harrell, Frank E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654113/
https://www.ncbi.nlm.nih.gov/pubmed/19290050
http://dx.doi.org/10.1371/journal.pone.0004922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654113/
https://www.ncbi.nlm.nih.gov/pubmed/19290050
http://dx.doi.org/10.1371/journal.pone.0004922

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