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Factors Influencing the Statistical Power of Complex Data Analysis Protocols for Molecular Signature Development from Microarray Data
BACKGROUND: Critical to the development of molecular signatures from microarray and other high-throughput data is testing the statistical significance of the produced signature in order to ensure its statistical reproducibility. While current best practices emphasize sufficiently powered univariate...
Autores principales: | Aliferis, Constantin F., Statnikov, Alexander, Tsamardinos, Ioannis, Schildcrout, Jonathan S., Shepherd, Bryan E., Harrell, Frank E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654113/ https://www.ncbi.nlm.nih.gov/pubmed/19290050 http://dx.doi.org/10.1371/journal.pone.0004922 |
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