Myostatin Inhibition in Muscle, but Not Adipose Tissue, Decreases Fat Mass and Improves Insulin Sensitivity

Myostatin (Mstn) is a secreted growth factor expressed in skeletal muscle and adipose tissue that negatively regulates skeletal muscle mass. Mstn(−/−) mice have a dramatic increase in muscle mass, reduction in fat mass, and resistance to diet-induced and genetic obesity. To determine how Mstn deleti...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Tingqing, Jou, William, Chanturiya, Tatyana, Portas, Jennifer, Gavrilova, Oksana, McPherron, Alexandra C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654157/
https://www.ncbi.nlm.nih.gov/pubmed/19295913
http://dx.doi.org/10.1371/journal.pone.0004937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654157/
https://www.ncbi.nlm.nih.gov/pubmed/19295913
http://dx.doi.org/10.1371/journal.pone.0004937

Ejemplares similares