Integrin α3β1–dependent β-catenin phosphorylation links epithelial Smad signaling to cell contacts

Injury-initiated epithelial to mesenchymal transition (EMT) depends on contextual signals from the extracellular matrix, suggesting a role for integrin signaling. Primary epithelial cells deficient in their prominent laminin receptor, α3β1, were found to have a markedly blunted EMT response to TGF-β...

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Detalles Bibliográficos
Autores principales: Kim, Young, Kugler, Matthias C., Wei, Ying, Kim, Kevin K., Li, Xiaopeng, Brumwell, Alexis N., Chapman, Harold A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654298/
https://www.ncbi.nlm.nih.gov/pubmed/19171760
http://dx.doi.org/10.1083/jcb.200806067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654298/
https://www.ncbi.nlm.nih.gov/pubmed/19171760
http://dx.doi.org/10.1083/jcb.200806067

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