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Integrin α3β1–dependent β-catenin phosphorylation links epithelial Smad signaling to cell contacts
Injury-initiated epithelial to mesenchymal transition (EMT) depends on contextual signals from the extracellular matrix, suggesting a role for integrin signaling. Primary epithelial cells deficient in their prominent laminin receptor, α3β1, were found to have a markedly blunted EMT response to TGF-β...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654298/ https://www.ncbi.nlm.nih.gov/pubmed/19171760 http://dx.doi.org/10.1083/jcb.200806067 |