Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

Peripheral blood neutrophils form highly decondensed chromatin structures, termed neutrophil extracellular traps (NETs), that have been implicated in innate immune response to bacterial infection. Neutrophils express high levels of peptidylarginine deiminase 4 (PAD4), which catalyzes histone citrull...

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Detalles Bibliográficos
Autores principales: Wang, Yanming, Li, Ming, Stadler, Sonja, Correll, Sarah, Li, Pingxin, Wang, Danchen, Hayama, Ryo, Leonelli, Lauriebeth, Han, Hyunsil, Grigoryev, Sergei A., Allis, C. David, Coonrod, Scott A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654299/
https://www.ncbi.nlm.nih.gov/pubmed/19153223
http://dx.doi.org/10.1083/jcb.200806072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654299/
https://www.ncbi.nlm.nih.gov/pubmed/19153223
http://dx.doi.org/10.1083/jcb.200806072

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