Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas

Reactive oxygen species (ROS) increase ligation of Fas (CD95), a receptor important for regulation of programmed cell death. Glutathionylation of reactive cysteines represents an oxidative modification that can be reversed by glutaredoxins (Grxs). The goal of this study was to determine whether Fas...

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Detalles Bibliográficos
Autores principales: Anathy, Vikas, Aesif, Scott W., Guala, Amy S., Havermans, Marije, Reynaert, Niki L., Ho, Ye-Shih, Budd, Ralph C., Janssen-Heininger, Yvonne M.W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654302/
https://www.ncbi.nlm.nih.gov/pubmed/19171757
http://dx.doi.org/10.1083/jcb.200807019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654302/
https://www.ncbi.nlm.nih.gov/pubmed/19171757
http://dx.doi.org/10.1083/jcb.200807019

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