The SCF(Slimb) ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication

Restricting centriole duplication to once per cell cycle is critical for chromosome segregation and genomic stability, but the mechanisms underlying this block to reduplication are unclear. Genetic analyses have suggested an involvement for Skp/Cullin/F box (SCF)-class ubiquitin ligases in this proc...

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Detalles Bibliográficos
Autores principales: Rogers, Gregory C., Rusan, Nasser M., Roberts, David M., Peifer, Mark, Rogers, Stephen L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654306/
https://www.ncbi.nlm.nih.gov/pubmed/19171756
http://dx.doi.org/10.1083/jcb.200808049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654306/
https://www.ncbi.nlm.nih.gov/pubmed/19171756
http://dx.doi.org/10.1083/jcb.200808049

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