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A Dialogue between the Hypoxia-Inducible Factor and the Tumor Microenvironment

The hypoxia-inducible factor is the key protein responsible for the cellular adaptation to low oxygen tension. This transcription factor becomes activated as a result of a drop in the partial pressure of oxygen, to hypoxic levels below 5% oxygen, and targets a panel of genes involved in maintenance...

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Detalles Bibliográficos
Autores principales: Dayan, Frédéric, Mazure, Nathalie M., Brahimi-Horn, M. Christiane, Pouysségur, Jacques
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654353/
https://www.ncbi.nlm.nih.gov/pubmed/19308685
http://dx.doi.org/10.1007/s12307-008-0006-3