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A Dialogue between the Hypoxia-Inducible Factor and the Tumor Microenvironment
The hypoxia-inducible factor is the key protein responsible for the cellular adaptation to low oxygen tension. This transcription factor becomes activated as a result of a drop in the partial pressure of oxygen, to hypoxic levels below 5% oxygen, and targets a panel of genes involved in maintenance...
Autores principales: | Dayan, Frédéric, Mazure, Nathalie M., Brahimi-Horn, M. Christiane, Pouysségur, Jacques |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654353/ https://www.ncbi.nlm.nih.gov/pubmed/19308685 http://dx.doi.org/10.1007/s12307-008-0006-3 |
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