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Upregulation of α7 Nicotinic Receptors by Acetylcholinesterase C-Terminal Peptides

BACKGROUND: The alpha-7 nicotinic acetylcholine receptor (α7-nAChR) is well known as a potent calcium ionophore that, in the brain, has been implicated in excitotoxicity and hence in the underlying mechanisms of neurodegenerative disorders such as Alzheimer's disease. Previous research implied...

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Detalles Bibliográficos
Autores principales: Bond, Cherie E., Zimmermann, Martina, Greenfield, Susan A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654408/
https://www.ncbi.nlm.nih.gov/pubmed/19287501
http://dx.doi.org/10.1371/journal.pone.0004846