Engineering the vaccinia virus L1 protein for increased neutralizing antibody response after DNA immunization

BACKGROUND: The licensed smallpox vaccine, comprised of infectious vaccinia virus, has associated adverse effects, particularly for immunocompromised individuals. Therefore, safer DNA and protein vaccines are being investigated. The L1 protein, a component of the mature virion membrane that is conse...

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Detalles Bibliográficos
Autores principales: Shinoda, Kaori, Wyatt, Linda S, Irvine, Kari R, Moss, Bernard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654435/
https://www.ncbi.nlm.nih.gov/pubmed/19257896
http://dx.doi.org/10.1186/1743-422X-6-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654435/
https://www.ncbi.nlm.nih.gov/pubmed/19257896
http://dx.doi.org/10.1186/1743-422X-6-28

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